atomoxetine hydrochloride
The hydrochloride salt of atomoxetine, a phenoxy-3-propylamine derivative and selective non-stimulant, norepinephrine reuptake inhibitor with cognitive-enhancing activity. Although its precise mechanism of action is unknown, atomoxetine appears to selectively inhibit the pre-synaptic norepinephrine transporter, resulting in inhibition of the presynaptic reabsorption of norepinephrine and prolongation of norepinephrine activity in the synaptic cleft; the effect on cognitive brain function may result in improved attention and decreased impulsivity and activity levels.
| Synonym: | tomoxetine |
|---|---|
| US brand name: | Strattera |
| Chemical structure: | (-)-N -methyl-3-phenyl-3-(o-tolyloxy)-propylamine hydrochloride (-)-N-methyl-gamma(2-methylphenoxy)benzenepropamine Hydrochloride |