NCI Drug Dictionary

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The NCI Drug Dictionary contains technical definitions and synonyms for drugs/agents used to treat patients with cancer or conditions related to cancer. Each drug entry includes links to check for clinical trials listed in NCI's List of Cancer Clinical Trials.

recombinant human EGF-rP64K/Montanide ISA 51 vaccine
A peptide vaccine preparation, containing recombinant human epidermal growth factor (rEGF) linked to the Neisseria meningitidis-derived recombinant immunogenic carrier protein P64k (rP64k) and mixed with the immunoadjuvant Montanide ISA 51, with potential active immunotherapy activity. Recombinant human EGF-rP64K/Montanide ISA 51 vaccine may trigger a humoral immune response against vaccine rEGF and rP64K and, so, against endogenous EGF. Antibody-mediated inhibition of endogenous EGF binding to its receptor, epithelial growth factor receptor (EGFR), may result in the inhibition of tumor cell proliferation. Check for active clinical trials using this agent. (NCI Thesaurus)

Synonym:Center of Molecular Immunology (CIMA) epidermal growth factor (EGF) vaccine
Center of Molecular Immunology epidermal growth factor vaccine
CIMAvax epidermal growth factor vaccine
recombinant human EGF-P64K/Montanide vaccine