NCI Drug Dictionary
The NCI Drug Dictionary contains technical definitions and synonyms for drugs/agents used to treat patients with cancer or conditions related to cancer. Each drug entry includes links to check for clinical trials listed in NCI's List of Cancer Clinical Trials.
- heparan sulfate glycosaminoglycan mimetic nanopolymer mouthwash
A nanopolymer-based mouthwash formulation containing a mimetic of the glycosaminoglycan (GAG) heparan sulfate, with potential anti-mucositic and protective activities. Upon rinsing with the mouthwash, GAGs bind to heparan sulfate binding sites on macromolecules within the extracellular matrix (EMC), which prevents the destruction of the ECM and protects both growth factors and cytokines from being degraded. By replacing the GAGs damaged by chemotherapy and/or radiation, this mouthwash may protect healthy tissue against the cytotoxic effects of chemotherapy and radiation and may prevent against radiotherapy- and chemotherapy-induced mucositis. Check for active clinical trials using this agent. (NCI Thesaurus)
Foreign brand name: MUCIPLIQ