Skip to main content
An official website of the United States government
Español
Government Funding Lapse
Because of a lapse in government funding, the information on this website may not be up to date, transactions submitted via the website may not be processed, and the agency may not be able to respond to inquiries until appropriations are enacted.

The NIH Clinical Center (the research hospital of NIH) is open. For more details about its operating status, please visit cc.nih.gov.

Updates regarding government operating status and resumption of normal operations can be found at opm.gov.

late or variable onset

(layt … VAYR-ee-uh-bul …)
Refers to the age at which a disease phenotype is expressed in an individual who carries a pathogenic variant. Conditions with late or variable onset generally manifest later in life or at no fixed time over the course of a lifetime.
Search NCI's Dictionary of Genetics Terms