NCI Dictionary of Genetics Terms

The NCI Dictionary of Genetics Terms contains technical definitions for more than 200 terms related to genetics. These definitions were developed by the PDQ® Cancer Genetics Editorial Board to support the evidence-based, peer-reviewed PDQ cancer genetics information summaries.

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propositus
(proh-PAH-zih-tus)
The male individual through whom a family with a genetic disorder is ascertained. In females this is called a proposita.