2015 - RAS Dialogue Blog
-
The RAS Reference Reagents Program: Sharing Resources and Enabling RAS Research
Dominic Esposito describes how the preparation of highly qualified reagents for use in the RAS Initiative also supports research in the broader RAS community
-
More Evidence That a Wild-Type KRAS Allele Plays a Role in Cancer
Jim Hartley of the RAS Initiative discusses evidence from mouse models that a wild type KRAS allele modulates early selection of Q61L or Q61R mutants in lung cancers.
-
Ras Mitogenic Signaling: p53 Enters the Stage
Mariano Barbacid and Matthias Drosten describe experiments that reveal a new role for the p53/p21Clp1/Rb axis in controling MAPK signaling.
-
Targeting Ras Membrane Association: Still an Achilles Heel
Mark Philips reviews attempts to drug KRAS, and to influence its translocation to the plasma membrane.
-
RAS Pathway v2.0
Frank McCormick, scientific lead of the RAS Initiative, incorporates over 30 suggestions from the RAS community to formulate an updated version of the RAS pathway, v2.0