A form of the anticancer drug doxorubicin that is contained in very tiny, fat-like particles. It may have fewer side effects and work better than doxorubicin. Doxorubicin hydrochloride liposome is used to treat ovarian cancer, AIDS-related Kaposi sarcoma, and multiple myeloma in patients whose disease has not gotten better after treatment with other anticancer drugs. It may be used together with other anticancer drugs. It is also being studied in the treatment of other types of cancer. Doxorubicin hydrochloride liposome is a type of anthracycline antitumor antibiotic. Also called Dox-SL, Doxil, Evacet, LipoDox, and liposomal doxorubicin hydrochloride.