A drug used in
certain patients to treat squamous cell cancer of the head
and neck and classical Hodgkin lymphoma.
Nivolumab is also used to treat
certain types of melanoma, non-small cell lung cancer,
renal cell carcinoma (a type of kidney cancer), and
urothelial carcinoma (a type of bladder cancer). It is also
being studied in the treatment of other types of cancer.
Nivolumab binds to a protein
called PD-1, which is found on T cells (a type of white
blood cell). Nivolumab may block
PD-1 and help the immune system kill cancer cells. It is a
type of monoclonal antibody and a type of immune checkpoint
inhibitor. Also called Opdivo.