Clinical Trials for Complementary or Alternative Medicine Procedure(s)

Trials 1-25 of 65
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  • Efficacy of MBSR Treatment of Cognitive Impairment Among Breast Cancer Survivors

    The purpose of this study is to evaluate MBSR(BC), an intensive meditation-based stress reduction intervention, in order to determine its efficacy in improving cognitive functioning among breast cancer survivors. The study will employ a three group randomized design that will (1) evaluate the extent to which MBSR(BC) compared to the Breast Cancer-Education Support (BCES) program or Usual Care (UC) improves cognitive functioning among breast cancer survivors off treatment; (2) determine if improvements in cognitive functioning achieved from MBSR(BC) are mediated through increased mindfulness and decreased rumination and stress; (3) evaluate genetic variants as moderators of MBSR(BC) on improvements in CI; and (4) determine the impact of MBSR(BC) on healthcare utilization and costs, in addition it will be delivered to a sub-group in Spanish. If shown to be efficacious, the possibility exists of utilizing this intervention in other types of cancers as well as non-cancer health-related disorders in order to minimize the morbidity experienced by these populations.
    Location: Moffitt Cancer Center, Tampa, Florida

  • Acupuncture in Treating Dry Mouth Caused by Radiation Therapy in Patients with Head and Neck Cancer

    This randomized phase III trial studies acupuncture to see how well it works compared to sham acupuncture or standard therapy in treating dry mouth caused by radiation therapy (xerostomia) in patients with head and neck cancer. Acupuncture may help relieve dry mouth caused by radiation therapy.
    Location: 30 locations

  • Personalized Electroacupuncture Therapy or Battle Field Acupuncture Therapy in Reducing Musculoskeletal Pain in Patients with Non-metastatic Cancer

    This randomized clinical trial studies how well personalized electroacupuncture therapy or battle field acupuncture therapy works in reducing pain that originates in the bones, muscles, tendons, or ligaments in patients with cancer that has not spread to other parts of the body. Electroacupuncture therapy or battle field acupuncture therapy may help relieve chronic pain caused by cancer and may help guide the personalized delivery of acupuncture for patients with chronic pain.
    Location: 7 locations

  • Physical Activity in Reducing Functional Health Disparities in Older Stage I-III Breast Cancer Survivors

    This randomized phase III trial studies physical activity in reducing functional health disparities in older stage I-III breast cancer survivors. Increased physical activity among older breast cancer survivors may help to improve functional and overall health status.
    Location: 5 locations

  • Mindfulness Education in Reducing Active Surveillance Stress in Participants with Prostate Cancer and Their Spouses

    This trial studies how well mindfulness education works in reducing surveillance stress in participants with prostate cancer and their spouses. Mindfulness education may help to reduce the effects of active surveillance stress, uncertainty, and rumination.
    Location: 5 locations

  • Acupuncture and Pain Counseling in Reducing Pain and Symptom Distress in Hospitalized Cancer Patients

    This trial studies how well acupuncture and pain counseling work in reducing pain and symptoms distress in hospitalized patients with cancer. Acupuncture uses thin needles placed along specific points to reduce pain. Pain counselling may be an effective method to help patients learn about pain management. Non-pharmacologic approaches such as acupuncture and pain counseling may broaden pain management options to help in providing comprehensive care for diverse patients with cancer.
    Location: 3 locations

  • Mechanisms of Active Music Engagement in Managing Acute Distress and in Improving Positive Health Outcomes in Young Children with Cancer and Their Parents

    This early phase I trial studies the mechanisms of active music engagement (AME) in managing acute distress and in improving positive health outcomes in young children with cancer and their parents. AME includes a variety of music play activities and may help decrease parent and young child distress and improve quality of life during cancer treatment.
    Location: 3 locations

  • 3RP-AYA Intervention in Reducing Stress and Promoting Stress Management in Adolescent and Young Adult Cancer Survivors

    This trial studies the feasibility and acceptability of Relaxation Response Resiliency Program for adolescent and young adult (3RP-AYA) intervention in reducing stress and promoting stress management in adolescent and young adult who have completed treatment for cancer within the past five years. 3RP-AYA intervention uses a variety of mind-body approaches, such as imagery, relaxation, and yoga that may buffer stress and promote psychological resiliency and physical well-being in adolescent and young adult cancer survivors.
    Location: 2 locations

  • Mindfulness-Music Intervention in Reducing Anxiety and Stress in Adolescents and Young Adults Receiving Cancer Treatment

    This trial studies how well a mindfulness-music intervention works in reducing anxiety and stress in adolescents and young adults receiving cancer treatment. A program designed to incorporate music-based meditation practices and music making activities (e.g., guitar, drums) may help to promote relaxation during cancer treatment.
    Location: 2 locations

  • Pain Management Support Study for Patients With Advanced Cancer

    Chronic pain is one of the most feared symptoms in people with cancer. Insufficient relief from pharmacological treatments and the fear of side effects are important reasons for the growing use of complementary pain management approaches in cancer care. On such approach is music therapy. Although several studies have demonstrated that music therapy interventions can reduce pain in people with cancer, few studies have examined the therapeutic mechanisms that explain how music therapy interventions lead to improved pain management. The purpose of this study is to examine whether an interactive music therapy intervention improves psychological and social factors that play an important role in chronic pain management in people with advanced cancer. The findings will contribute towards the optimization of music therapy for palliation of chronic pain in people with advanced cancer.
    Location: 2 locations

  • Acupressure in Decreasing Treatment-Related Symptoms in Childhood Cancer Patients

    This randomized pilot phase III trial studies how well acupressure works in decreasing treatment-related symptoms in childhood cancer patients. Acupressure may reduce treatment-related symptoms and help patients feel better.
    Location: 2 locations

  • Yoga in Treating Chemotherapy-Induced Peripheral Nerve Damage in Stage I-III Breast, Ovarian, Uterine, or Endometrial Cancer Survivors

    This pilot randomized clinical trial compares the effectiveness of yoga on reducing symptoms caused by chemotherapy-induced nerve damage in stage I-III breast, ovarian, uterine, or endometrial cancer survivors. Yoga may help relieve pain and reduce symptoms from peripheral neuropathy caused by chemotherapy in breast cancer survivors.
    Location: 2 locations

  • Mindfulness Meditation or Survivorship Education in Improving Behavioral Symptoms in Younger Stage 0-III Breast Cancer Survivors (Pathways to Wellness)

    This randomized phase III trial studies how well mindfulness meditation or survivorship education work in improving behavioral symptoms in younger stage 0-III breast cancer survivors. Behavioral interventions, such as mindfulness meditation, use techniques to help patients change the way they react to environmental triggers that may cause a negative reaction. Survivorship education after treatment may reduce stress and improve the well-being and quality of life of patients with breast cancer. Mindfulness meditation or survivorship education may help improve the health behaviors of younger breast cancer survivors.
    Location: 3 locations

  • Using SMART Design to Improve Symptom Management Strategies Among Cancer Patients

    In order to optimize symptom management, there must be a shift from fixed interventions "one size fits all" to adaptive interventions tailored to individual patients. Our multistaged interventions use the sequential multiple assignment randomized trial (SMART) design. This design will operationalize the decision rules for switching from one intervention to another for individual patients. Our team's work to date with breast and lung cancer patients has shown efficacy for two home-based symptom management interventions, reflexology and meditative practices, delivered by or with friend or family caregivers. The sustainability of use of these two evidence based therapies and improvements in symptom outcomes will be tested during weeks 5-8 and at the week 12 follow up of 331 patients based on power analysis, against a control group. By sequencing two evidence based interventions, the proposed research will impact research and practice by determining how to maximize the benefit of symptom management during cancer treatment.
    Location: 2 locations

  • Dyadic Yoga Intervention in Improving Physical Performance and Quality of Life in Patients with Stage I-III Non-small Cell Lung Cancer Undergoing Radiotherapy and Their Caregivers

    This trial studies how well dyadic yoga intervention works in improving physical performance and quality of life in patients with stage I-III non-small cell lung cancer undergoing radiotherapy and their caregivers. Dyadic yoga intervention may help to improve physical function, fatigue, sleep difficulties, depressive symptoms, and overall quality of life for patients with non-small cell lung cancer and / or their caregivers.
    Location: M D Anderson Cancer Center, Houston, Texas

  • Yoga in Improving Chronic Pain in Patients with Chemotherapy-Induced Peripheral Neuropathy

    This trial studies how well yoga works in improving painful chemotherapy-induced peripheral neuropathy that has persisted for at least three months after the completion of chemotherapy treatment. Yoga intervention may help patients with chronic painful chemotherapy-induced peripheral neuropathy by improving symptoms that co-occur with pain (such as fatigue, anxiety) and strength and balance.
    Location: Dana-Farber Cancer Institute, Boston, Massachusetts

  • Spiritual Care Assessment and Intervention Framework in Supporting Patients with Advanced Cancer and Their Caregivers

    This trial studies how well a religious and spiritual tool called spiritual care assessment and intervention (SCAI) framework works in supporting the emotional and spiritual well being of patients with cancer that has spread to other places in the body and their caregivers. SCAI framework is an approach to spiritual care delivered by skilled chaplains, that covers the spiritual dimensions of meaning and purpose, relationships, peace, and self-worth and identity. Participating in the SCAI framework may enable doctors to examine a participant’s spiritual strengths and distress and find out the most effective spiritual care intervention for that participant.
    Location: Indiana University / Melvin and Bren Simon Cancer Center, Indianapolis, Indiana

  • Acupuncture Therapy in Reducing Hot Flashes in Patients with Estrogen Receptor Positive Stage I-III Breast Cancer

    This trial studies how well acupuncture therapy works in reducing hot flashes in patients with estrogen receptor positive stage I-III breast cancer. Hot flashes are a common side effect of breast cancer treatment and are felt as a sensation of sudden onset body warmth, flushing, and sweating. Acupuncture is a complementary therapy in which, hair-thin, sterile disposable needles are inserted into various spots on the skin, with the goal of affecting the body’s natural healing system. Acupuncture may help to reduce the number and intensity of hot flashes in breast cancer patients who are being treated with medications such as tamoxifen and aromatase inhibitors.
    Location: Dana-Farber Cancer Institute, Boston, Massachusetts

  • Animal-Assisted Interactions in Improving Quality of Life in Children with Advanced, Relapsed, or Refractory Cancer and Their Parents

    This trial studies how well animal-assisted interactions work in improving quality of life in children with cancer that has spread extensively to other anatomic sites or is no longer responding to treatment, has come back, or does not respond to treatment, and their parents. Having animal-assisted therapy (AAT) visits on a routine basis with a trained animal-handler and his / her dog may help to make the cancer treatment process less stressful for children and their parents.
    Location: Vanderbilt University / Ingram Cancer Center, Nashville, Tennessee

  • Tai Ji Quan, Strength Training, or Stretching for Fall Prevention and Functional Improvements in Patients with Prostate Cancer Receiving Antiandrogen Therapy

    This trial studies the use of tai ji quan, strength training, or stretching for fall prevention and improvements in physical function in patients with prostate cancer receiving antiandrogen therapy. Treatments for prostate cancer can cause side effects such as fatigue, muscle loss, and weakness which can increase the risk of falls and frailty. Group exercise training using tai ji quan, strength training, or stretching for improving balance, strength, and mobility may improve physical function, mood, and overall quality of life in patients with prostate cancer.
    Location: OHSU Knight Cancer Institute, Portland, Oregon

  • Online Psychosocial Intervention in Improving Social Well-Being and Support in Women with Stage I-IV Non-small Cell Lung Cancer Undergoing Treatment

    This trial studies how well online psychosocial intervention works in improving social well-being and support in women who are undergoing treatment for stage I-IV non-small cell lung cancer. Psychosocial intervention techniques, such as mindfulness, compassion, and emotional processing, may improve distress and help patients manage symptoms related to non-small cell lung cancer.
    Location: M D Anderson Cancer Center, Houston, Texas

  • Eischens Yoga in Reducing Fatigue and Stress Levels in Patients with Stage I-II Cancer

    This early phase I trial studies how well yoga works in reducing fatigue and stress levels in patients with stage I-II cancer. Yoga decreases pain, reduces stress, and has been shown to improve sleep quality, energy, and physical functioning. Eischens yoga specifically incorporates ideas from movement theory, kinesiology, and Ayurveda, and is more focused on the energy of poses rather than doing more complex poses.
    Location: University of Pennsylvania / Abramson Cancer Center, Philadelphia, Pennsylvania

  • Art in Improving Outcomes in Patients Undergo Surgery

    This trial studies how well art works in improving outcomes in patients who are undergoing surgery. Exposure to art may help to improve clinical and psychological outcomes.
    Location: Roswell Park Cancer Institute, Buffalo, New York

  • Music in Reducing Distress in Patients with Cancer during Chemotherapy Treatment

    This trial studies how well music works in reducing distress in patients with cancer during chemotherapy treatment. Music in participants receiving cancer treatment such as infusion treatment and caregiver may reduce pain, anxiety, and distress and improve patient's psychological and physiological wellbeing.
    Location: Wayne State University / Karmanos Cancer Institute, Detroit, Michigan

  • Mindfulness-Based Stress Reduction in Helping Participants with Metastatic Breast Cancer

    This randomized trial studies how well a mindfulness-based stress reduction program helps participants with breast cancer that has spread to other places in the body. A cancer diagnosis is a life-changing and highly stressful event for most people, often resulting in marked declines in quality of life both during and after treatment. There are approximately 3 million women living with a history of invasive breast cancer in the U.S., with at least 150,000 living with metastatic disease. Patient preferences suggest a high need for complementary and alternative medicine interventions to address these chronic symptoms. Mindfulness-based stress reduction programs may help women living with metastatic breast cancer manage symptoms related to cancer treatment and improve quality of life.
    Location: Roswell Park Cancer Institute, Buffalo, New York


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