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CSSI Research Areas and Programs

The Center for Strategic Scientific Initiatives (CSSI) coordinates a range of programs in collaboration with NCI Divisions, Offices, and Centers and with other federal agencies and partners. Programs span technology development, emerging and cross-disciplinary science, and scientific workforce support. Below is a list of selected programs coordinated by CSSI. 

  • Innovative Molecular Analysis Technologies (IMAT)

    The IMAT grant program supports research projects aimed at developing innovative technologies to advance cancer research and clinical care.

  • Informatics Technology for Cancer Research (ITCR)

    The ITCR program supports informatics technology development driven by critical needs in cancer research though funding opportunities tailored to successive stages of the informatics technology development lifecycle.

  • COnsortium of METabolomics Studies (COMETS)

    COMETS promotes collaborations among prospective cohort studies and builds data infrastructure for studies in metabolomic epidemiology.

  • Big Data Scientist Training Enhancement Program (BD-STEP)

    The NCI/Veterans Health Administration’s BD-STEP supports training of early career scientists using VA’s rich healthcare data resources. Fellows with quantiative expertise are matched to VA medical centers and partner with clinicians to use data science to address important questions in cancer research and care.

  • Synthetic Biology and Cancer

    NCI and the National Institute of Biomedical Imaging and Bioengineering (NIBIB) collaborate on the Synthetic Biology and Cancer Program which supports innovative applications of synthetic biology technologies to address challenges across cancer biology, prevention, early detection, diagnosis, and treatment.

  • Cancer Grand Challenges

    NCI and Cancer Research UK (CRUK), the world's leading funders in cancer research, partner to fund the Cancer Grand Challenges (CGC) program. CGC supports novel ideas from multi-national interdisciplinary research teams to address some of cancer's toughest challenges.

  • Imaging Mass Cytometry (IMC) Laboratory

    The IMC Laboratory provides cancer researchers access to high-dimensional imaging analysis. Through resources and expertise at the Frederick National Laboratory for Cancer Research, investigators can submit project proposals to complement ongoing cancer research with spatial biology studies using the IMC technology.

  • NCI Serological Sciences Network for COVID-19 (SeroNet)

    SeroNet was developed in response to the COVID-19 global pandemic through a congressional appropriation to NCI to develop, validate, improve, and implement serological testing and associated technologies.

  • NCI Research Specialist Award (R50)

    NCI's R50 Award provides salary support and travel funds for exceptional scientists including those in research labs and core facilities that are pursuing research within the context of an existing cancer research program.

  • The NCI Outstanding Investigator Award (R35)

    NCI's Outstanding Investigator Award supports accomplished leaders in cancer research who are providing significant contributions toward understanding cancer and developing tools that may lead to breakthroughs in biomedical, behavioral, or clinical cancer research.

  • Past CSSI Programs

    Past programs coordinated by the Center for Strategic Scientific Initiatives