NCI Dictionary of Cancer Terms

The NCI Dictionary of Cancer Terms features 8,354 terms related to cancer and medicine.

We offer a widget that you can add to your website to let users look up cancer-related terms. Get NCI’s Dictionary of Cancer Terms Widget.

Browse:
NEDD8-activating enzyme inhibitor
(… AK-tih-vay-ting EN-zime in-HIH-bih-ter)
A substance that blocks an enzyme called NEDD8-activating enzyme (NAE). NAE is involved in important cell functions, such as cell division. Blocking NAE may help keep cancer cells from growing and may kill them. Some NEDD8-activating enzyme inhibitors are being studied in the treatment of cancer. They are a type of targeted therapy. Also called NAE inhibitor.