NCI Dictionary of Cancer Terms

The NCI Dictionary of Cancer Terms features 8,442 terms related to cancer and medicine.

We offer a widget that you can add to your website to let users look up cancer-related terms. Get NCI’s Dictionary of Cancer Terms Widget.

NAE inhibitor
(… in-HIH-bih-ter)
A substance that blocks an enzyme called NEDD8-activating enzyme (NAE). NAE is involved in important cell functions, such as cell division. Blocking NAE may help keep cancer cells from growing and may kill them. Some NAE inhibitors are being studied in the treatment of cancer. They are a type of targeted therapy. Also called NEDD8-activating enzyme inhibitor.