NCI Dictionary of Cancer Terms
The NCI Dictionary of Cancer Terms features 8,385 terms related to cancer and medicine.
We offer a widget that you can add to your website to let users look up cancer-related terms. Get NCI’s Dictionary of Cancer Terms Widget.
- IDH1 gene
- listen (… jeen)
- A gene that makes a protein called isocitrate dehydrogenase 1 (IDH1). The IDH1 protein helps break down fats for energy and protect cells from harmful molecules. Mutations (changes) in the IDH1 gene have been found in several genetic conditions and in some types of cancer, including acute myelogenous leukemia, myelodysplastic syndromes, and brain cancer. These changes may cause abnormal cells, including cancer cells, to grow and spread in the body. Also called isocitrate dehydrogenase-1 gene.