NCI Dictionary of Cancer Terms

The NCI Dictionary of Cancer Terms features 8,442 terms related to cancer and medicine.

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NTRK gene fusion
(… jeen FYOO-zhun)
A mutation (change) that occurs when a piece of the chromosome containing a gene called NTRK breaks off and joins with a gene on another chromosome. NTRK gene fusions lead to abnormal proteins called TRK fusion proteins, which may cause cancer cells to grow. NTRK gene fusions may be found in some types of cancer, including cancers of the brain, head and neck, thyroid, soft tissue, lung, and colon. Also called neurotrophic tyrosine receptor kinase gene fusion.