NCI Dictionary of Cancer Terms

The NCI Dictionary of Cancer Terms features 8,545 terms related to cancer and medicine.

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basket trial
(BAS-ket TRY-ul)
A type of clinical trial that tests how well a new drug or other substance works in patients who have different types of cancer that all have the same mutation or biomarker. In basket trials, patients all receive the same treatment that targets the specific mutation or biomarker found in their cancer. Basket trials may allow new drugs to be tested and approved more quickly than traditional clinical trials. Basket trials may also be useful for studying rare cancers and cancers with rare genetic changes. Also called bucket trial.