NCI Dictionary of Cancer Terms

The NCI Dictionary of Cancer Terms features 8,468 terms related to cancer and medicine.

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ado-trastuzumab emtansine
(A-doh-tras-TOO-zoo-mab em-TAN-seen)
A drug used to treat HER2-positive breast cancer. It is used in certain patients who have already been treated with an anticancer drug called trastuzumab and a type of drug called a taxane. It is also being studied in the treatment of other types of cancer. Ado-trastuzumab emtansine contains a monoclonal antibody called trastuzumab that binds to a protein called HER2, which is found on some breast cancer cells. It also contains an anticancer drug called DM1, which may help kill cancer cells. Ado-trastuzumab emtansine is a type of antibody-drug conjugate. Also called Kadcyla and T-DM1.