NCI Dictionary of Cancer Terms

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The NCI Dictionary of Cancer Terms features 8,260 terms related to cancer and medicine.

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aggressive systemic mastocytosis
(uh-GREH-siv sis-TEH-mik MAS-toh-sy-TOH-sis)
A rare condition in which too many mast cells (a type of white blood cell) build up in certain tissues and organs in the body, including the bone marrow, lymph nodes, bone, liver, spleen, and small intestine. Aggressive systemic mastocytosis may get worse quickly and cause severe symptoms and organ damage. Sometimes, it may become mast cell leukemia (a very rare type of leukemia). Aggressive systemic mastocytosis usually occurs in adults. Also called ASM.