NCI Dictionary of Cancer Terms

The NCI Dictionary of Cancer Terms features 8,322 terms related to cancer and medicine.

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anti-CD22 immunotoxin CAT-8015
(AN-tee … IH-myoo-noh-TOK-sin …)
A drug used to treat hairy cell leukemia that came back or did not get better with at least two other systemic therapies, including treatment with a purine nucleoside analog (a type of anticancer drug). Anti-CD22 immunotoxin CAT-8015 contains a monoclonal antibody called moxetumomab that binds to a protein called CD22, which is found on B cells (a type of white blood cell) and some types of leukemia cells. It also contains a bacterial toxin called PE38, which may help kill cancer cells. Anti-CD22 immunotoxin CAT-8015 is a type of immunotoxin. Also called CAT-8015, Lumoxiti, and moxetumomab pasudotox.