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c-erbB-2 positive

(… PAH-zih-tiv)
Describes cells that have a protein called HER2 on their surface. In normal cells, HER2 helps control cell growth. Cancer cells that make too much HER2 may grow more quickly and are more likely to spread to other parts of the body. Checking to see if a cancer is c-erbB-2 positive may help plan treatment, which may include drugs that kill c-erbB-2-positive cancer cells. Cancers that may be c-erbB-2 positive include breast, bladder, pancreatic, ovarian, and stomach cancers. Also called HER2 positive and human epidermal growth factor receptor 2 positive.
Search NCI's Dictionary of Cancer Terms