NCI Dictionary of Cancer Terms

The NCI Dictionary of Cancer Terms features 8,290 terms related to cancer and medicine.

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chimeric antigen receptor
(ky-MEER-ik AN-tih-jen reh-SEP-ter)
A special receptor created in the laboratory that is designed to bind to certain proteins on cancer cells. The chimeric antigen receptor is then added to immune cells called T cells. This helps the T cells find and kill cancer cells that have the specific protein that the receptor is designed to bind. These changed T cells called chimeric antigen receptor T cells are then grown in large numbers in the laboratory and given to cancer patients. Chimeric antigen receptor T cells are being studied in the treatment of some types of cancer. Also called CAR.