NCI Dictionary of Cancer Terms
The NCI Dictionary of Cancer Terms features 8,492 terms related to cancer and medicine.
We offer a widget that you can add to your website to let users look up cancer-related terms. Get NCI’s Dictionary of Cancer Terms Widget.
- chimeric antigen receptor T-cell therapy
- listen (ky-MEER-ik AN-tih-jen reh-SEP-ter T-sel THAYR-uh-pee)
A type of treatment in which a patient's T cells (a type of immune system cell) are changed in the laboratory so they will attack cancer cells. T cells are taken from a patient’s blood. Then the gene for a special receptor that binds to a certain protein on the patient’s cancer cells is added in the laboratory. The special receptor is called a chimeric antigen receptor (CAR). Large numbers of the CAR T cells are grown in the laboratory and given to the patient by infusion. Chimeric antigen receptor T-cell therapy is being studied in the treatment of some types of cancer. Also called CAR T-cell therapy.