NCI Dictionary of Cancer Terms

The NCI Dictionary of Cancer Terms features 8,531 terms related to cancer and medicine.

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denileukin diftitox
(DEH-nih-LOO-kin DIF-tih-tox)
A drug used to treat cutaneous T-cell lymphoma that has recurred (come back) or has not gotten better with other treatment. It is used in patients whose cancer has a receptor for the protein interleukin-2 (IL-2). It is also being studied in the treatment of other types of cancer. Denileukin diftitox is made by combining IL-2 with a bacterial toxin. The IL-2 part of the drug attaches to the cancer cells and the toxin kills them. Denileukin diftitox is a type of immunotoxin and a type of fusion protein. Also called Ontak.