NCI Dictionary of Cancer Terms

The NCI Dictionary of Cancer Terms features 8,531 terms related to cancer and medicine.

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dexrazoxane hydrochloride
(DEX-ruh-ZOK-sane HY-droh-KLOR-ide)
A drug used to treat severe side effects caused by certain anticancer drugs. It is used under the brand name Totect to treat the toxic effects of an anticancer drug that leaks from a vein into surrounding tissue and causes tissue damage. It is also used under the brand name Zinecard to reduce heart damage in women given doxorubicin for breast cancer that has spread to other parts of the body. Dexrazoxane hydrochloride is also being studied in the treatment of some types of cancer. It is a type of cardioprotective agent, a type of chemoprotective agent, and a type of topoisomerase inhibitor. Dexrazoxane is the active ingredient of dexrazoxane hydrochloride.