Skip to main content
An official website of the United States government
Español
Government Funding Lapse
Because of a lapse in government funding, the information on this website may not be up to date, transactions submitted via the website may not be processed, and the agency may not be able to respond to inquiries until appropriations are enacted.

The NIH Clinical Center (the research hospital of NIH) is open. For more details about its operating status, please visit cc.nih.gov.

Updates regarding government operating status and resumption of normal operations can be found at opm.gov.

DHFR inhibitor

(… in-HIH-bih-ter)
A substance that can build up in cancer cells and block them from using folate. Folate is a nutrient that rapidly dividing cells need to make DNA. Blocking folate use helps keep cancer cells from growing and may kill them. Some DHFR inhibitors are used to treat cancer. A DHFR inhibitor is a type of antifolate. Also called dihydrofolate reductase inhibitor.
Search NCI's Dictionary of Cancer Terms