NCI Dictionary of Cancer Terms

The NCI Dictionary of Cancer Terms features 8,614 terms related to cancer and medicine.

We offer a widget that you can add to your website to let users look up cancer-related terms. Get NCI’s Dictionary of Cancer Terms Widget.

gestational trophoblastic disease
(jeh-STAY-shuh-nul troh-fuh-BLAS-tik dih-ZEEZ)
A rare condition in which abnormal cells grow inside the uterus from tissue that forms after conception (the joining of sperm and egg). This tissue is made of trophoblastic cells, which normally surround the fertilized egg in the uterus and help connect the fertilized egg to the wall of the uterus. These cells also form part of the placenta (the organ that passes nutrients from the mother to the fetus). Most gestational trophoblastic diseases are benign (not cancer) and do not spread, but some types are malignant (cancer) and spread to nearby tissues or other parts of the body. The two main types of gestational trophoblastic diseases are hydatidiform mole and choriocarcinoma. Also called gestational trophoblastic tumor, GTD, and GTT.