NCI Dictionary of Cancer Terms

The NCI Dictionary of Cancer Terms features 8,492 terms related to cancer and medicine.

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imatinib mesylate
(ih-MA-tih-nib MEH-zih-layt)
A drug used to treat certain types of leukemia and other blood cancers. It is also used to treat gastrointestinal stromal tumors (GIST), skin tumors called dermatofibrosarcoma protuberans, and a rare condition called systemic mastocytosis. It is also being studied in the treatment of other types of cancer. Imatinib mesylate blocks the protein made by the BCR-ABL oncogene, which may help keep cancer cells from growing and may kill them. Imatinib mesylate is a type of tyrosine kinase inhibitor. Also called Gleevec and STI571.