isocitrate dehydrogenase-2 gene
(I-soh-SIH-trayt dee-hy-DRAH-jeh-nays … jeen)
A gene that
makes a protein that is found inside small structures in
cells called mitochondria and that helps the mitochondria
make energy for many cell functions. Mutations (changes) in
the isocitrate dehydrogenase-2 gene have been found in
certain genetic conditions and in some types of cancer,
including acute myelogenous leukemia and brain cancer.
These changes may cause abnormal cells, including cancer
cells, to grow and spread in the body. Also called IDH2 gene.