NCI Dictionary of Cancer Terms

The NCI Dictionary of Cancer Terms features 8,442 terms related to cancer and medicine.

We offer a widget that you can add to your website to let users look up cancer-related terms. Get NCI’s Dictionary of Cancer Terms Widget.

niraparib tosylate monohydrate
(nih-RA-puh-rib TOH-suh-layt MAH-noh-HY-drayt)
A drug used to treat recurrent ovarian epithelial, fallopian tube, or primary peritoneal cancers that have gotten better after treatment with anticancer drugs that included platinum. Niraparib tosylate monohydrate is used to help keep the cancer from coming back again. It is also being studied in the treatment of other types of cancer. Niraparib tosylate monohydrate blocks an enzyme involved in many cell functions, including the repair of DNA damage. Blocking this enzyme may help keep cancer cells from repairing their damaged DNA, causing them to die. Niraparib tosylate monohydrate is a type of poly (ADP-ribose) polymerase inhibitor. Also called Zejula.