Government Funding Lapse
Because of a lapse in government funding, the information on this website may not be up to date, transactions submitted via the website may not be processed, and the agency may not be able to respond to inquiries until appropriations are enacted.

The NIH Clinical Center (the research hospital of NIH) is open. For more details about its operating status, please visit cc.nih.gov.

Updates regarding government operating status and resumption of normal operations can be found at opm.gov.

germline mutation

(JERM-line myoo-TAY-shun)

A mutation in a reproductive cell (egg or sperm) that is in the DNA of every cell in the offspring's body. A mutation contained within the germline can be passed from parent to offspring and is, therefore, hereditary. Also called germline variant.

germline mutation

Search NCI's Dictionary of Genetics Terms