NCI Dictionary of Genetics Terms

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The NCI Dictionary of Genetics Terms contains technical definitions for more than 200 terms related to genetics. These definitions were developed by the PDQ® Cancer Genetics Editorial Board to support the evidence-based, peer-reviewed PDQ cancer genetics information summaries.

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tumor suppressor gene
(TOO-mer suh-PREH-ser jeen)
A type of gene that regulates cell growth. When a tumor suppressor gene is mutated, uncontrolled cell growth may occur. This may contribute to the development of cancer. Also called antioncogene.