NCI Dictionary of Genetics Terms
The NCI Dictionary of Genetics Terms contains technical definitions for more than 200 terms related to genetics. These definitions were developed by the PDQ® Cancer Genetics Editorial Board to support the evidence-based, peer-reviewed PDQ cancer genetics information summaries.
- HLOD score
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- A statistical estimate of whether two genetic loci are physically near enough to each other (or “linked”) on a particular chromosome that they are likely to be inherited together. An HLOD score is calculated in the presence of locus heterogeneity (when the same phenotype can be caused by mutations in genes at different chromosomal loci). Also called heterogeneity logarithm of the odds score.