NCI Dictionary of Genetics Terms

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The NCI Dictionary of Genetics Terms contains technical definitions for more than 200 terms related to genetics. These definitions were developed by the PDQ® Cancer Genetics Editorial Board to support the evidence-based, peer-reviewed PDQ cancer genetics information summaries.

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heterogeneity logarithm of the odds score
(HEH-teh-roh-jeh-NEE-ih-tee LAW-guh-RIH-thum … skor)
A statistical estimate of whether two genetic loci are physically near enough to each other (or “linked”) on a particular chromosome that they are likely to be inherited together. A heterogeneity logarithm of the odds score is calculated in the presence of locus heterogeneity (when the same phenotype can be caused by mutations in genes at different chromosomal loci). Also called HLOD score.