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NCI Dictionary of Genetics Terms

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The NCI Dictionary of Genetics Terms contains technical definitions for more than 200 terms related to genetics. These definitions were developed by the PDQ® Cancer Genetics Editorial Board to support the evidence-based, peer-reviewed PDQ cancer genetics information summaries.

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logarithm of the odds score
(LAW-guh-RIH-thum … skor)
A statistical estimate of whether two genetic loci are physically near enough to each other (or "linked") on a particular chromosome that they are likely to be inherited together. A logarithm of the odds score of 3 or higher is generally understood to mean that two genes are located close to each other on the chromosome. In terms of significance, a logarithm of the odds score of 3 means the odds are 1,000:1 that the two genes are linked and therefore inherited together. Also called LOD score.