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2025 Childhood Cancer Data Initiative Webinars

Childhood Cancer Data Initiative (CCDI) webinars communicate the initiative’s goals and activities, highlight progress, and demonstrate how to find and use CCDI web applications, platforms, and data.

If you missed a webinar, access past recordings and presentations below.

2026 | 2025 | 2024 | 2023

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December 9, 2025: Advancing Precision Oncology for Retinoblastoma Through Liquid Biopsy

This webinar focuses on the development of a novel aqueous humor liquid biopsy platform for Retinoblastoma. The platform addresses a long-standing barrier in pediatric oncology by enabling safe, repeatable molecular analysis of tumor-derived cell-free DNA from the eye.

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September 9, 2025: Exploring ecDNA's Impact on Childhood Cancers

This webinar focuses on the prevalence and clinical significance of circular extrachromosomal DNA (ecDNA) in childhood cancers, the impact of recurrently amplified oncogenes, the evolution of ecDNA during disease progression, and how these insights can inform future ecDNA-directed therapies. 

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August 12, 2025: Mutational Epidemiology of Childhood Cancer

This webinar discusses the data sources and methods of analysis for childhood cancer tumor data and present preliminary risk factor associations with molecular subtypes and MutSig in acute lymphoblastic leukemia and ependymoma.

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May 13, 2025: Pre-clinical Evaluation of Targeted Therapies for Pediatric Cancer

This webinar explores Pediatric Preclinical in Vivo Testing (PIVOT), an NCI-funded program evaluating targeted cancer therapies developed for adult oncology to determine if they have relevance to childhood cancers. Topics covered include mission and history, lessons learned, past and recent multi-modal omics characterization of human-in-mouse tumors, and how to access relevant genomic and efficacy study data.

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January 14, 2025: Unlock the Power of Unstructured Data with EMERSE

This webinar introduces EMERSE, a text processing system designed specifically for non-technical users. It shows how the system can help you efficiently work with free text (unstructured data) from electronic health record systems.

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