This page contains brief information about amifostine and a collection of links to more information about the use of this drug, research results, and ongoing clinical trials.
Use in Cancer
Amifostine is approved to prevent:
- Renal (kidney) toxicity. It is used to reduce the nephrotoxic effects caused by repeated treatment with cisplatin for advanced ovarian cancer.
- Xerostomia (dry mouth). It is used to decrease dryness in the mouth caused by radiation therapy after surgery in some patients with head and neck cancer.
Amifostine is also being studied in the treatment of other types of cancer.
More About Amifostine
Definition from the NCI Drug Dictionary - Detailed scientific definition and other names for this drug.
MedlinePlus Information on Amifostine - A lay language summary of important information about this drug that may include the following:
- warnings about this drug,
- what this drug is used for and how it is used,
- what you should tell your doctor before using this drug,
- what you should know about this drug before using it,
- other drugs that may interact with this drug, and
- possible side effects.
Drugs are often studied to find out if they can help treat or prevent conditions other than the ones they are approved for. This patient information sheet applies only to approved uses of the drug. However, much of the information may also apply to unapproved uses that are being studied.
Clinical Trials Accepting Patients
Find Clinical Trials for Amifostine - Check for trials from NCI's list of cancer clinical trials now accepting patients.