This page contains brief information about avelumab and a collection of links to more information about the use of this drug, research results, and ongoing clinical trials.
Use in Cancer
Avelumab is approved to treat:
- Merkel cell carcinoma that has metastasized (spread to other parts of the body). It is used in adults and in children aged 12 years or older.
- Renal cell carcinoma (a type of kidney cancer) that is advanced. It is used with axitinib as first-line therapy.
- Urothelial carcinoma (a type of bladder cancer) that is locally advanced or has metastasized. It is used in patients whose disease got worse during or after treatment with platinum chemotherapy.
These uses are approved under FDA’s Accelerated Approval Program. As a condition of approval, confirmatory trial(s) must show that avelumab provides a clinical benefit in these patients.
Avelumab is also being studied in the treatment of other types of cancer.
More About Avelumab
Definition from the NCI Drug Dictionary - Detailed scientific definition and other names for this drug.
MedlinePlus Information on Avelumab - A lay language summary of important information about this drug that may include the following:
- warnings about this drug,
- what this drug is used for and how it is used,
- what you should tell your doctor before using this drug,
- what you should know about this drug before using it,
- other drugs that may interact with this drug, and
- possible side effects.
Drugs are often studied to find out if they can help treat or prevent conditions other than the ones they are approved for. This patient information sheet applies only to approved uses of the drug. However, much of the information may also apply to unapproved uses that are being studied.
Research Results and Related Resources
Clinical Trials Accepting Patients
Find Clinical Trials for Avelumab - Check for trials from NCI's list of cancer clinical trials now accepting patients.