Bevacizumab

(beh-vuh-SIH-zoo-mab)

This page contains brief information about bevacizumab and a collection of links to more information about the use of this drug, research results, and ongoing clinical trials.

US Brand Name(s)

Avastin

FDA Approved

Yes

FDA Approval for Bevacizumab

Use in Cancer

Bevacizumab is approved to be used alone or with other drugs to treat:

Cervical cancer that has not gotten better with other treatment, has metastasized (spread to other parts of the body), or has recurred (come back).
Colorectal cancer that has metastasized.
Glioblastoma (a type of brain cancer) in patients whose disease has not gotten better with other treatment.
Non-small cell lung cancer that is locally advanced, cannot be removed by surgery, has metastasized, or has recurred.
Ovarian epithelial, fallopian tube, or primary peritoneal cancer that has recurred. It is used in patients whose disease does not respond to platinum chemotherapy.
Renal cell cancer that has metastasized.

Bevacizumab is also being studied in the treatment of other types of cancer.

More About Bevacizumab

Definition from the NCI Drug Dictionary - Detailed scientific definition and other names for this drug.

MedlinePlus Information on Bevacizumab - A lay language summary of important information about this drug that may include the following:

warnings about this drug,
what this drug is used for and how it is used,
what you should tell your doctor before using this drug,
what you should know about this drug before using it,
other drugs that may interact with this drug, and
possible side effects.

Drugs are often studied to find out if they can help treat or prevent conditions other than the ones they are approved for. This patient information sheet applies only to approved uses of the drug. However, much of the information may also apply to unapproved uses that are being studied.

Targeted Cancer Therapies - Information about the use of this drug to treat cancer.

Biological Therapies for Cancer - Information about the use of this drug to treat cancer.

Research Results

Clinical Trial Results: Combining Chemotherapy with Bevacizumab Improves Outcomes for Ovarian Cancer Patients - Important clinical trial results for this drug, background information, and how the trial was done.

Clinical Trial Results: When Combined with Chemotherapy, Bevacizumab Is Associated with Increased Risk of Death - Important clinical trial results for this drug, background information, and how the trial was done.

Bevacizumab Significantly Improves Survival for Patients with Recurrent and Metastatic Cervical Cancer - Information from the NCI Press Office about this drug.

Clinical Trials Accepting Patients

Find Clinical Trials for Bevacizumab - Check for trials from NCI's list of cancer clinical trials now accepting patients.