This page contains brief information about bevacizumab and a collection of links to more information about the use of this drug, research results, and ongoing clinical trials.
Use in Cancer
Bevacizumab is approved to be used alone or with other drugs to treat:
- Cervical cancer that has not gotten better with other treatment, has metastasized (spread to other parts of the body), or has recurred (come back). It is used with paclitaxel and either cisplatin or topotecan hydrochloride. This use is approved for the Avastin, Zirabev, and Mvasi brands of bevacizumab.
- Colorectal cancer that has metastasized. It is used:
- Glioblastoma (a type of brain cancer) that has recurred. It is used in adults. This use is approved for the Avastin, Zirabev, and Mvasi brands of bevacizumab.
- Hepatocellular carcinoma (a type of liver cancer) that is metastatic or cannot be removed by surgery. It is used with atezolizumab in patients who have not received systemic therapy. This use is approved for the Avastin brand of bevacizumab.
- Nonsquamous non-small cell lung cancer that is locally advanced, cannot be removed by surgery, has metastasized, or has recurred. It is used with carboplatin and paclitaxel as first-line therapy. This use is approved for the Avastin, Zirabev, and Mvasi brands of bevacizumab.
- Ovarian epithelial, fallopian tube, or primary peritoneal cancer. It is used with other drugs in patients with stage III, stage IV, or recurrent disease. This use is approved for the Avastin brand of bevacizumab.
- Renal cell carcinoma (a type of kidney cancer) that has metastasized. It is used with interferon alpha. This use is approved for the Avastin, Zirabev, and Mvasi brands of bevacizumab.
Bevacizumab is also being studied in the treatment of other types of cancer.
More About Bevacizumab
Definition from the NCI Drug Dictionary - Detailed scientific definition and other names for this drug.
MedlinePlus Information on Bevacizumab - A lay language summary of important information about this drug that may include the following:
- warnings about this drug,
- what this drug is used for and how it is used,
- what you should tell your doctor before using this drug,
- what you should know about this drug before using it,
- other drugs that may interact with this drug, and
- possible side effects.
Drugs are often studied to find out if they can help treat or prevent conditions other than the ones they are approved for. This patient information sheet applies only to approved uses of the drug. However, much of the information may also apply to unapproved uses that are being studied.
Research Results and Related Resources
Clinical Trials Accepting Patients
Find Clinical Trials for Bevacizumab - Check for trials from NCI's list of cancer clinical trials now accepting patients.