Erdafitinib is a type of targeted therapy called an enzyme inhibitor. It blocks the action of an abnormal protein on the surface of some cancer cells. This may keep cancer cells from growing and may kill them.
Use in Cancer
Erdafitinib is approved to treat:
- Urothelial carcinoma (a type of bladder cancer) that has spread or cannot be removed by surgery and has certain mutations in the FGFR3 gene or a fusion gene involving the FGFR3 gene or FGFR2 gene. It is used in adults whose cancer got worse during or after treatment with at least one type of platinum chemotherapy.
Erdafitinib is also being studied in the treatment of other types of cancer.
More About Erdafitinib
Definition from the NCI Drug Dictionary - Detailed scientific definition and other names for this drug.
MedlinePlus Information on Erdafitinib - A lay language summary of important information about this drug that may include the following:
- warnings about this drug,
- what this drug is used for and how it is used,
- what you should tell your doctor before using this drug,
- what you should know about this drug before using it,
- other drugs that may interact with this drug, and
- possible side effects.
Drugs are often studied to find out if they can help treat or prevent conditions other than the ones they are approved for. This patient information sheet applies only to approved uses of the drug. However, much of the information may also apply to unapproved uses that are being studied.
Research Results and Related Resources
Clinical Trials Accepting Patients
Find Clinical Trials for Erdafitinib - Check for trials from NCI's list of cancer clinical trials now accepting patients.