Ivosidenib
This page contains brief information about ivosidenib and a collection of links to more information about the use of this drug, research results, and ongoing clinical trials.
FDA label information for this drug is available at DailyMed.
Use in Cancer
Ivosidenib is approved to treat adults whose cancer has a certain mutation in the IDH1 gene, including:
- Acute myeloid leukemia (AML). It is used:
- Alone or with azacitidine in patients with newly-diagnosed cancer who are aged 75 years and older or who, due to health problems, cannot receive intensive induction chemotherapy.
- When the cancer has come back or has not gotten better after previous treatment.
- Cholangiocarcinoma (bile duct cancer) that has spread. It is used in adults whose cancer has been treated.
Ivosidenib is also being studied in the treatment of other types of cancer.
More About Ivosidenib
Definition from the NCI Drug Dictionary - Detailed scientific definition and other names for this drug.
MedlinePlus Information on Ivosidenib - A lay language summary of important information about this drug that may include the following:
- warnings about this drug,
- what this drug is used for and how it is used,
- what you should tell your doctor before using this drug,
- what you should know about this drug before using it,
- other drugs that may interact with this drug, and
- possible side effects.
Drugs are often studied to find out if they can help treat or prevent conditions other than the ones they are approved for. This patient information sheet applies only to approved uses of the drug. However, much of the information may also apply to unapproved uses that are being studied.
Research Results and Related Resources
Ivosidenib with Chemotherapy New Option for Some People with AML
Clinical Trials Accepting Patients
Find Clinical Trials for Ivosidenib - Check for trials from NCI's list of cancer clinical trials now accepting patients.