This page contains brief information about larotrectinib sulfate and a collection of links to more information about the use of this drug, research results, and ongoing clinical trials.
Use in Cancer
Larotrectinib sulfate is approved to treat:
- Solid tumors that have an NTRK gene fusion without a drug-resistance mutation in certain TRK proteins. It is used in adults and children whose cancer has metastasized (spread to other parts of the body) or cannot be removed by surgery and has gotten worse after other treatment or cannot be treated with other therapies.
Larotrectinib sulfate is also being studied in the treatment of other types of cancer.
More About Larotrectinib Sulfate
Definition from the NCI Drug Dictionary - Detailed scientific definition and other names for this drug.
MedlinePlus Information on Larotrectinib Sulfate - A lay language summary of important information about this drug that may include the following:
- warnings about this drug,
- what this drug is used for and how it is used,
- what you should tell your doctor before using this drug,
- what you should know about this drug before using it,
- other drugs that may interact with this drug, and
- possible side effects.
Drugs are often studied to find out if they can help treat or prevent conditions other than the ones they are approved for. This patient information sheet applies only to approved uses of the drug. However, much of the information may also apply to unapproved uses that are being studied.
Research Results and Related Resources
Clinical Trials Accepting Patients
Find Clinical Trials for Larotrectinib Sulfate - Check for trials from NCI's list of cancer clinical trials now accepting patients.