Mitomycin is an antibiotic used as a chemotherapy drug. It stops or slows the growth of cancer cells and other rapidly growing cells by damaging their DNA.
Use in Cancer
Mitomycin is approved to be used alone or with other drugs to treat:
- Gastric (stomach) and pancreatic adenocarcinoma that is locally advanced or has metastasized (spread to other parts of the body). It is used in patients whose disease has not gotten better with other types of treatment.
- Urothelial cancer in the upper urinary tract. It is given directly into the ureter or kidney as a treatment for adults with low-grade disease. This use is approved for the Jelmyto brand of mitomycin.
Mitomycin is also being studied in the treatment of other types of cancer.
More About Mitomycin
Definition from the NCI Drug Dictionary - Detailed scientific definition and other names for this drug.
- warnings about the drug,
- what the drug is used for and how it is used,
- what you should tell your doctor before using the drug,
- what you should know about the drug before using it,
- other drugs that may interact with the drug, and
- possible side effects.
Drugs are often studied to find out if they can help treat or prevent conditions other than the ones they are approved for. This patient information sheet applies only to approved uses of the drug. However, much of the information may also apply to unapproved uses that are being studied.
Clinical Trials Accepting Patients
Find Clinical Trials for Mitomycin - Check for trials from NCI's list of cancer clinical trials now accepting patients.