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Ramucirumab works by blocking a protein called VEGFR-2, which some cancer cells produce in large amounts. Blocking VEGFR-2 may prevent the growth of new blood vessels that tumors need to grow. Ramucirumab is a type of targeted therapy drug called an angiogenesis inhibitor.

US Brand Name(s)
FDA Approved

FDA label information for this drug is available at DailyMed.

Use in Cancer

Ramucirumab is approved to be used alone or with other drugs to treat:

Ramucirumab is also being studied in the treatment of other types of cancer.

More About Ramucirumab

Definition from the NCI Drug Dictionary - Detailed scientific definition and other names for this drug.

MedlinePlus Information on Ramucirumab - A lay language summary of important information about this drug that may include the following:

  • warnings about this drug,
  • what this drug is used for and how it is used,
  • what you should tell your doctor before using this drug,
  • what you should know about this drug before using it,
  • other drugs that may interact with this drug, and
  • possible side effects.

Drugs are often studied to find out if they can help treat or prevent conditions other than the ones they are approved for. This patient information sheet applies only to approved uses of the drug. However, much of the information may also apply to unapproved uses that are being studied.

Research Results and Related Resources

Targeted Therapy to Treat Cancer

Monoclonal Antibodies

Immune Checkpoint Inhibitors

Angiogenesis Inhibitors

Clinical Trials Accepting Patients

Find Clinical Trials for Ramucirumab - Check for trials from NCI's list of cancer clinical trials now accepting patients.

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