This page contains brief information about selpercatinib and a collection of links to more information about the use of this drug, research results, and ongoing clinical trials.
Use in Cancer
Selpercatinib is approved to treat:
- Medullary thyroid cancer that has a certain mutation in the RET gene and has spread. It is used in adults and children aged 12 years and older who need systemic therapy.¹
- Non-small cell lung cancer that has a RET fusion gene and has spread. It is used in adults.
- Solid tumors that have a RET fusion gene and have spread. It is used in adults whose cancer got worse during or after systemic therapy or whose cancer cannot be treated with other therapies.¹
- Thyroid cancer that has a RET fusion gene and has spread. It is used in adults and children aged 12 years and older who need systemic therapy, including those who received radioactive iodine and it did not work or is no longer working.¹
Selpercatinib is also being studied in the treatment of other types of cancer.
More About Selpercatinib
Definition from the NCI Drug Dictionary - Detailed scientific definition and other names for this drug.
MedlinePlus Information on Selpercatinib - A lay language summary of important information about this drug that may include the following:
- warnings about this drug,
- what this drug is used for and how it is used,
- what you should tell your doctor before using this drug,
- what you should know about this drug before using it,
- other drugs that may interact with this drug, and
- possible side effects.
Drugs are often studied to find out if they can help treat or prevent conditions other than the ones they are approved for. This patient information sheet applies only to approved uses of the drug. However, much of the information may also apply to unapproved uses that are being studied.
Research Results and Related Resources
Clinical Trials Accepting Patients
Find Clinical Trials for Selpercatinib - Check for trials from NCI's list of cancer clinical trials now accepting patients.