Data Generation and Collection
Identify and gather the data you need to address a problem.
- Beginner
- [Article] Generating and Collecting Data: The Basics | Get the fundamentals on what it is, why it matters, and how you can do it effectively.
- [Training Video Recording] Genomic Data Commons Data Portal | Watch a tutorial on how this web-based platform allows you to search, analyze, and download data from cancer genomics studies. | Recorded Nov. 7, 2024
- [Training Video Recording] Unlocking Insights from Clinical Notes with the EMERSE Text Processing Tool | Use this tool to identify key data within free-text clinical notes from electronic health records systems. | Recorded Sept. 30, 2024
- [Training Video Recording] The Cancer Proteome Atlas | Get an introduction to RPPA (a high-throughput, antibody-based technique for protein profiling); receive an overview of the bioinformatics resource, “The Cancer Proteome Atlas” (or TCPA); and learn more about TCPA’s chatbot, “TCPAplus.” | Recorded Sept. 13, 2024
- [Training Video Recording] GARDE: Open-Source Platform for Population-based Genetic Testing of Hereditary Cancer Syndromes | Learn how to facilitate population-based genetic testing with the GARDE software platform, which harnesses algorithms and chatbots to identify individuals eligible for genetic testing for hereditary cancer syndromes. | Recorded July 25, 2024
- [Training Video Recording] Data Management and Planning: Getting Started | Learn the fundamentals of data management, including how to define key stakeholders and outline plans. | Recorded Dec. 5, 2023
- Advanced
- [Training Video Recording] WebMeV | Discover how to use this intuitive, web-based, bioinformatics analysis toolkit designed for non-bioinformaticians. This walkthrough includes steps on how to upload data files, run a single-cell analysis (using the tools available within the toolkit), and how to navigate/create public data sets available within WebMeV. | Recorded Jan. 31, 2023
Data Cleaning
Fix discrepancies and handle missing values in your data.
- Beginner
- [Article] Cleaning Data: The Basics | Get the fundamentals on what it is, why it matters, and how you can do it effectively.
Data Exploration and Analysis
Study your data, then form a hypothesis.
- Beginner
- [Article] Exploring and Analyzing Data: The Basics | Get the fundamentals on what it is, why it matters, and how you can do it effectively.
- [Article] How to Use the Cancer Data Aggregator | Read about this resource and how it can help you in your search for data across NCI's Cancer Research Data Commons.
- [Article] Copy Number Variation (CNV) Calling: The Basics | Get tips on generating CNV data and how to choose the right tool.
- [Article] Spatial Transcriptomics (ST): The Basics | Describes the basics of using ST for cancer research, including spotlighting an NCI-funded tool that doesn’t require specialized skills in bioinformatics.
- [Training Video Recording] Multiomic Data Analysis with Illumina | Learn about the “Illumina Connected Multiomics” tool and see how it can help you calculate statistics and create interactive visualizations, regardless of your bioinformatics experience level. | Recorded Aug. 13, 2026
- [Training Video Recording] Unveiling FlowJo Version 11 | Discover FlowJo with a modern language code base. This version makes visual comparisons faster to access, it comes with more built-in automation tools, and it’s built on a foundation compatible with cloud computer. | Recorded Jan. 8, 2026
- [Training Video Recording] Introduction to FlowJo™ Software | Learn about FlowJo’s workspace—including how to load files, evaluate sample quality, draw gates, and generate tabular and graphical layouts to perform single-cell flow cytometry analysis. | Recorded Sept. 18, 2024
- [Training Video Recording] An Introduction to Bioconductor for Genomic Data Science | Learn the basics of integrative data containers for genome-scale experiments and components of analytic workflows for transcriptomics and epigenetics. You will also discover resources for annotation of genomic data. | Recorded Aug. 23, 2024
- [Training Video Recording] RNAseq Data Analysis in Qlucore | Import and analyze RNA-sequencing data in Qlucore Omics Explorer—software that visualizes the data in 3D plots and can help you identify hidden structures and patterns. | Recorded Aug. 14, 2024
- [Training Video Recording] User-Friendly Analysis of Spatial Transcriptomics with spatialGE | Learn more about this user-friendly web application that integrates the spatial R package. This package, enhanced with additional ST analysis methods (such as SpaGCN, STdeconvolve, and InSituType), makes it more valuable for the cancer research community. | Recorded Jun. 18, 2024
- [Training Video Recording] WebMeV | Receive a demonstration on how this web-based software for genomic data analysis can upload data and perform various analyses such as normalization, clustering, and principal component analysis. | Recorded Apr. 26, 2024
- [Training Video Recording] XNAT | Learn about this open source imaging informatics software platform that enables data ingestion, curation, annotation, quality control, and computational workflows using Docker containers. | Recorded Apr. 22, 2024
- Advanced
- [Training Video Recording] AmpliconSuite: Enabling Analysis of Focal Amplifications in Cancer Genomics | Learn about the AmpliconSuite, an integrated toolkit for detecting and classifying extrachromosomal DNA, from a member of one of the 2022 NCI Grand Challenges teams. | Recorded Apr. 27, 2026
- [Training Video Recording] Using the Network Zoo Tools to Explore Biological Complexity and Its Consequences | Find out how you can use the Network Zoo Tools, a repository of computational tools, to tackle complex biological questions about gene regulation and network inference. | Recorded Feb. 19, 2026
- [Training Video Recording] HLA-Arena: Enabling Structure-Guided Pipelines for Personalized Cancer Immunotherapy Design | Study Human Leukocyte Antigens (HLA) in cancer with this computational platform that incorporates neoantigen markers and other bioinformatics pipelines. | Recorded Apr. 30, 2025
- [Training Video Recording] User-Friendly Analysis of ST with spatialGE | Get an overview of ST, discover how it’s advancing cancer research, and watch a demonstration of the spatialGE web application that can help you with your ST data analysis. | Recorded Mar. 19, 2025
- [Training Video Recording] QIAGEN Ingenuity Pathway Analysis (IPA) Webinar | Learn how to analyze large data sets (including RNA-sequencing and proteomics) using QIAGEN IPA to perform interactive core and pathway analyses. | Recorded Oct. 23, 2024
- [Training Video Recording] Decoding Epigenetic Complexity: Modeling Gene Regulation with the Cistrome Data Browser | Discover methods for integrating Cistrome Data Browser data into single cell ATAC-sequencing and RNA-sequencing multimodal analysis. | Recorded Jul. 18, 2024
- [Training Video Recordings] NCI’s Containers and Workflows Interest Group Webinar Series | Hear from presenters—across NCI CBIIT, NIH, industry, and academia—as they discuss how cloud computing and container technologies, workflows, and data pipelines could drive cancer data science. | Recorded Jun. 26, 2024
- [Training Video Recording] TumorDecon | Discover how digital cytometry methods and their applications assist in tumor research. | Recorded Apr. 19, 2024
- [Training Video Recording] TCIA Jupyter Learning Lab | Explore a variety of use cases for identifying The Cancer Imaging Archive (TCIA) data sets, and learn how to download them using Jupyter Notebooks. You’ll also learn how to utilize TCIA for data exploration and downloading data. | Recorded Dec. 11, 2023
- [Training Video Recording] An Introduction to Gene Set Enrichment Analysis (GSEA) and the Molecular Signatures Database (MSigDB) | Learn how the GSEA analysis tool operates, how to use MSigDB to compare your data against well annotated gene sets, and how to run GSEA with MSigDB. | Jun. 15, 2023
Predictive Modeling
Use computational tools like machine learning models to make predictions with your data.
- Beginner
- [Article] Predictive Modeling: The Basics | Get the fundamentals on what it is, why it matters, and how you can do it effectively.
- Advanced
- [Training Video Recording] Pixels to Predictions: Designing Computational Imaging AI to Enable Precision Medicine | Learn more about the use of AI in precision medicine, specifically focusing on the development of computational imaging tools for different patient pathways. | Recorded Mar. 26, 2025
Data Visualization
Communicate your data findings using interactive images, plots, and charts.
- Beginner
- [Article] Visualizing Data: The Basics | Get the fundamentals on what it is, why it matters, and how you can do it effectively.
- [Article] How to Use Circle Plots for Visualizing Multi-Omics Data | Get tips on ‘OmicCircos,’ an R-based program that lets you manage, analyze, and visualize your omics data.
- [Training Video Recording] Introduction to UCSC Xena: A Tool for Multi-omics Data & Associate Clinical and Phenotypic Annotations | Learn about the features and capabilities of the Xena platform for genomics visualization and analysis, including data loading, filtering, statistical analysis, single-cell analysis, and various visualization options. | Recorded Mar. 13, 2025
- [Training Video Recording] The Cancer Digital Slide Archive (CDSA) Webinar | Explore this open-source, web-based platform for storing, visualizing, and managing digitized whole slide images. The platform addresses the growing need for pathology data management within the biomedical research community, enabling you to explore large, histological data sets. | Recorded Oct. 29, 2024
- [Training Video Recording] The GenePattern Ecosystem for Cancer Genomics and Reproducible Research | Discover an environment for accessible and reproducible research that hosts hundreds of genomics analysis and visualization tools. GenePattern exists in a web-based format that requires no programming, along with extensive features for reproducibility and accessibility. | Recorded Jun. 27, 2024
- [Training Video Recording] MATLAB: Now What? Post-Processing AI Techniques for Enhanced Accuracy | Familiarize yourself with post-processing AI techniques. | Recorded May 29, 2024
- Advanced
- [Training Video Recording] Next-Generation Clustered Heat Maps (NG-CHMs) | Learn how NG-CHMs can help you navigate large omic databases, zoom in on patterns, access external metadata resources, produce high-resolution graphics, and save metadata for later use. NG-CHMs play a valuable role in NIH projects, encompassing phenotypic and genotypic data at DNA, RNA, protein, and metabolite levels in bulk and single-cell studies. | Recorded Jun. 20, 2024
- [Training Video Recording] DNASTAR Lasergene Software | Learn about this software and its applications in molecular biology, including topics such as enzyme labels, primer design, cloning processes, construct analysis, and clone verification using Sanger sequencing. | Recorded May 15, 2024
- [Training Video Recording] Data Visualization with R | Learn how to use the ggplot2 package in the programming language R to graph plots that can form the basis of analysis. Note: This video is one of six videos that make up a course series exclusive to NCI staff and provided by the Bioinformatics Training and Education Program. In this recording, R Studio is accessed via DNAnexus. | Recorded Apr. 13, 2023
Data Sharing
Accelerate discovery by making your data available to others.
- Beginner
- [Article] Sharing Data: The Basics | Get the fundamentals on what it is, why it matters, and how you can do it effectively.
- [Training Video Recording] Data Management and Planning: Introduction to the NIH Policy for Data Management and Sharing | Receive an overview of this NIH policy and an introduction to both NIH resources and data management planning tools. | Recorded May 31, 2024
- Advanced
- [Resources] Metadata Services for Cancer Research | Discover how to approach the Cancer Standards Registry and Repository (caDSR II) infrastructure, which helps investigators create and use data standards for cancer research.
- [Blog] Semantics Primer | Get a snapshot of how semantics help create shared and consistent meanings for data so they can be used/reused and shared with researchers.
- [Blog] A Deep Dive into Common Data Elements (CDEs) | Discover how CDEs help researchers like you define, map, use, and share data more efficiently.
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