CCG Updates and Insights
Featuring current topics in cancer genomics research and news and updates from CCG.
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Continuing Our Work in the Time of Two PandemicsCCG Director Lou Staudt reflects on two pandemics—COVID-19 and racial injustice—and resolves to use the scientific method to address health care disparities.
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Single-Cell Metabolic Analyses of the Tumor Microenvironment: Researcher Interview with Jason LocasaleDr. Jason Locasale discusses new insights into the metabolic programs of different cell types in the tumor microenvironment—something enabled by the single-cell RNA sequencing revolution. Looking at metabolism helps us understand the activity of specific immune cells and how a patient might respond to different treatments.
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Introducing the Personal Genomics PodcastPersonal Genomics is NCI’s premier podcast about people in cancer genomics research. On this narrative podcast, researchers will share their stories about what happens behind the scenes of research.
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DREAM Challenges, Precision Medicine Algorithms, and Perspectives on Cancer Genomics Research: December OCG e-NewsletterComputational challenges, a suite of algorithms for identifying effective cancer treatments, a scientist interview on translating genomics for precision medicine for cancer, and other highlights from the December 2019 edition of the Office of Cancer Genomics (OCG) e-Newsletter.
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Over 44,000 AACR Project GENIE Cases Available in the GDCNCI’s Genomic Data Commons (GDC) has released data for 44,756 cancer cases from AACR Project GENIE. By making this massive data set available through the GDC, AACR and their partners hope to expand the reach and potential impact of the project and accelerate precision oncology research.
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Genome-wide Cell-Free DNA Fragmentation: A Potential Low-Cost Cancer Screening MethodDr. Robert Scharpf and Dr. Victor Velculescu discuss using DNA fragmentation profiles to analyze cell-free DNA and detect cancer from liquid biopsies. The machine learning-based method they developed could serve as a low-cost screening tool for a wide range of cancers.
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All the Childhood Cancer Data in the GDC (So Far)Childhood cancer genomics data from NCI’s TARGET program available in the Genomic Data Commons, plus some other resources for childhood cancer research.
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Dissecting Cellular Heterogeneity, Electronic Notebooks, and Next-Gen Cancer Models: August OCG e-NewsletterSingle-cell RNA sequencing, using “electronic notebooks” for genomic analyses, next-generation cancer models, and other cancer genomics highlights from the August 2019 edition of the Office of Cancer Genomics (OCG) e-Newsletter.
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Longitudinal Data from the MMRF Released at the GDCResearchers can now access rich, longitudinal genomic and clinical data from the Multiple Myeloma Research Foundation (MMRF) at NCI's Genomic Data Commons. CCG Director Lou Staudt describes the collaboration with the MMRF in a guest blog post.
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Happy 3rd Birthday, Genomic Data Commons: Continued Data and Tool GrowthAt the Genomic Data Commons’ three year anniversary, Dr. Lou Staudt reflects on milestones reached and describes future goals for growing an interactive knowledge system for the cancer research community.