Implementation Science in Low- and Middle-Income Countries
The Center for Global Health (CGH) supports implementation science for cancer prevention and control in low- and middle-income countries (LMICs) and low-resource settings.
Impact
A key challenge to reducing the global burden of cancer, particularly among people in LMICs and other populations experiencing disparities, is the poor implementation of cancer prevention and control strategies that are known to work. Implementation science is the study of how to integrate evidence-based practices into routine health settings to improve a population’s health.
Key gaps currently exist between researchers, program implementers, and the populations they serve. Without bridging these gaps, the global impact of new scientific discoveries and evidence will be diminished. CGH invests in researching and addressing the challenges of implementing evidence-based interventions, tools, policies, and guidelines in low-resource settings.
Funded Research
CGH supports a growing portfolio of dissemination and implementation science for cancer control in LMICs through funding various opportunities.
Funded Grants for Implementation Science
| Grant Number | Project Leader(s) | Collaborating Institutions | Title | Country |
|---|---|---|---|---|
| Global Implementation Science for Equitable Cancer Control (GlobalISE Cancer Control, U54 Clinical Trial Optional) | ||||
| U54 CA284109 | Maria Fernandez; Martin Lajous; Karla Unger-Saldaña | The University of Texas Health Science Center at Houston; Instituto Nacional de Salud Publica (INSP)-Mexico; Instituto Nacional de Cancerología (INCAN)-Mexico | LISTOS for Cancer Control - Leveraging Implementation Science To Optimize Strategies for Cancer Control | Mexico |
| U54 CA284110 | Juliet Iwelunmor; Joseph Tucker; Oliver Ezechi | Washington University School of Medicine; The University of North Carolina at Chapel Hill; Nigerian Institute of Medical Research | US-Nigerian Cancer Control Center for Research on Implementation Science and Equity (C3-RISE) | Nigeria |
| U54 CA284036 | Michael H. Chung; Mohammed S. Ali | Emory University | Enhanced BReast and cErvical cAncer screening in Kenya THROUGH | Kenya |
| U54 CA284030 | Delivette Castor; Louise Kuhn; Nomonde Mbatani; Rakiya Saidu; Juanita Arendse; Rachel Shelton; Parisa Tehranifar | Columbia University Irving Medical Center; University of Cape Town; Columbia University Irving Medical Center | The Empilisweni Center for Women's Health - Advancing Implementation of Equitable Cervical Cancer Control | South Africa |
| Implementation Science for Cancer Control in People Living with HIV in Low- and Middle-Income Countries (U01 Clinical Trial Optional) | ||||
| U01 CA275053 | Rebecca G Nowak; Sylvia Adebajo | University of Maryland Baltimore; Institute of Human Virology, Nigeria | Integrated Model for the Prevention of Anal Cancer using Screen and Treat for HSIL (IMPACT) | Nigeria |
| U01 CA275113 | Lisa C Flowers; Oliver Ozechi; Olutosi Awolude; Laura Gaydos; Olabank Ogunsola | Emory University; APIN Public Health Initiatives Ltd/Gte | The CHESS (Community, Home-based Education, Screening Services) Strategy to Increase Cervical Cancer Control Access for HIV-positive Women in Nigeria | Nigeria |
| U01 CA275054 | Sujha Subramanian; Michael Mbizvo; Catherine Mwaba | Research Triangle Institute; Clinical and Radiation Oncology Society of Zambia (ZASCRO) | Integrated Delivery of Cancer Control Interventions for Adolescents and Young Adults Living with HIV in Zambia | Zambia |
| U01 CA275118 | Gregory Aarons; Echezona Ezeanolue | University of California, San Diego; University of Nigeria | ACCESS: Accelerating Cervical Cancer Elimination Through the Integration of Screen-and-treat Services | Nigeria |
| Surbhi Grover; Katharine Rendle | University of Pennsylvania; University of Botswana | Thibang Diphatlha: Testing Adaptive Strategies to Close the Gap from Cervical Cancer Diagnosis to Treatment in Botswana | Botswana | |
| U01 CA275048 | Manhattan E Charurat; Seth Himelhoch; Bontle Mbongwe | University of Maryland Baltimore; Botswana-UMSOM Health Initiative | Botswana Smoking Abstinence Reinforcement Trial (BSMART) | Botswana |
| U01 CA275033 | Jean Marie Hunleth; Michelle Silver | Washington University; Tropical Disease Research Centre | Leveraging HIV Infrastructure to Implement Cervical Cancer Prevention: A Study to Integrate HPV Vaccination in Adolescent HIV Clinics in Zambia | Zambia |
| U01 CA275129 | Lifang Hou; Jane Holl; Mamoudou Maiga | Northwestern University at Chicago; Jos University Teaching Hospital; University of Ibadan; Universite des Sciences, des Techniques et des Technologies | West Africa Self-Sampling HPV-based Cervical Cancer Control Program (WA-SS-HCCP) for WLWHA: Barriers, Challenges, and Needs | Nigeria and Mali |
| U01 CA275120 | Michael Chung | Emory University | ENHANcing CErvical cancer screening and treatment in women LIviNg with HIV in KenyA (ENHANCE LINKAge) | Kenya |
| U01 CA275117 | Gregory Kirk | Johns Hopkins University | Leveraging HIV care infrastructure for implementation of context-adapted liver cancer comprehensive control strategies in Uganda: The LC3 Study | Uganda |
| U01 CA294811 | Thanh Bui | University of Oklahoma Health Sciences Center | Implementing Sustainable mobile health Technology to Optimize smoking cessation Program for Lao people with HIV (I-STOP) | Laos |
| U01 CA294674 | Troy Moon | Tulane University of Louisiana | A hybrid type III effectiveness-implementation, pragmatic intervention trial for cervical cancer screen and treat in Mozambique | Mozambique |
| U01 CA294756 | Corrina Moucheraud | New York University | Kupewa: Optimizing strategies to implement provider recommendation of HPV vaccination for adolescent girls and young women with HIV in Malawi | Malawi |
| U01 CA294799 | Breanne Lott | Albert Einstein College of Medicine | Leveraging Project ECHO for improved cervical cancer screening in Ethiopia: An implementation study of integrated HPV self sampling in HIV care centers | Ethiopia |
| U01 CA294757 | Matt Asare | Baylor University | The Impact of an Evidence-Based, Behavioral Cervical Cancer Screening Intervention among Women Living with HIV in Ghana (HOPE-inG): A Type 2 Hybrid Effectiveness Implementation Trial | Ghana |
| U01 CA275110 | Rebecca Schnall | Columbia University | Implementation of Screen, Treat, and Triage for Women Living with HIV in La Romana (iSTAR) | Dominican Republic |
Additional Funded Research
How to Connect
CGH collaborates with NCI’s Division of Cancer Control and Population Sciences (DCCPS). For more information, see DCCPS’ Implementation Science team.
For more information about implementation science at CGH, please contact Dr. Margarita Correa-Méndez and Dr. Randiak Alaro.