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Implementation Science in Low- and Middle-Income Countries

Doctor with clipboard talking with a indigenous Peruvian woman
Credit: D. Snyder

The Center for Global Health (CGH) supports implementation science for cancer prevention and control in low- and middle-income countries (LMICs) and low-resource settings.


A key challenge to reducing the global burden of cancer, particularly among people in LMICs and other populations experiencing disparities, is the poor implementation of cancer prevention and control strategies that are known to work. Implementation science is the study of how to integrate evidence-based practices into routine health settings to improve a population’s health. 

Key gaps currently exist between researchers, program implementers, and the populations they serve. Without bridging these gaps, the global impact of new scientific discoveries and evidence will be diminished. CGH invests in researching and addressing the challenges of implementing evidence-based interventions, tools, policies, and guidelines in low-resource settings.

Funding Opportunities



Implementation Science Funding
Grant Number PI's/Project Leaders Collaborating Institutions Title Country
R01 CA24048 Donna Shelley, Nam Truong Nguyen New York University, Institute of Social and Medical Studies Implementing  Tobacco Use Treatment in HIV Clinics in Viet Nam Vietnam
R01 CA230355 Shoba Ramanadhan, Kasisomayajula Viswanath Dana-Farber Cancer Institute, Narotam Sekhsaria Fndn Adapting and Evaluating a Brief Advice Tobacco Intervention in High-reach, Low-resource Settings in India India
R01 CA258590 Nelly Mugo, Sarah Gimbel University of Washington, Kenya Medical Research Institute Towards Cervical Cancer Elimination: Implementation and Scale-up of a Single-visit Screen-and-treat Approach with Thermal Ablation for Sustainable Cervical Cancer Prevention Services in Kenya Kenya
R01CA262319 Ramzi Salloum, Rima Nakkash University of Florida, American University of Beirut Phone Enabled Implementation of Cessation Support (PHOENICS) Lebanon
R01CA271033 Juliet Iwelunmor, Oliver Ezechi, Joseph Tucker Saint Louis University, Nigerian Institutes of Medical Research Actions for Collaborative Community-Engaged Strategies for HPV (ACCESS HPV) Nigeria
R21CA267900  Donna Spiegelman
Yale University, National University of Mexico
Interventions to Increase Adherence to Cervical Cancer Early Detection and Treatment Recommendations in Mexico City Clinics Mexico
R01CA258683 Jon Andrew Dykens, Adama Fay University of Illinois Chicago, University Cheikh Anta Diop Adaptation and  implementation of a Patient Navigation program for Cervical Cancer Screening Across Contexts in Senegal Senegal
U01CA190366 J Kathleen Tracy, Valeria Pazsoldan University of Maryland, Asociacion Benefica Prisma Translating Molecular Diagnostics for Cervical Cancer Prevention into Practice Peru
R01CA278229 Carla J Berg, Michelle Kegle George Washington University, American University of Armenia, National Insititute of Health, Armenia; L Sakvarelidze National Center for Disease Control, Georgia Implementing a Scalable Smoke-free Home Intervention in Armenia and Georgia Armenia and Georgia
R37CA276215 Asya  Agulnik, Virginia McKay St. Jude Children's Research Hospital, 90 Hospitals in 20 countries in Latin America and Spain Sustainability Determinants of an Intervention to Identify Clinical Deterioration and Improve Childhood Cancer Survival in Low-resource Hospitals Argentina, Bolivia, Brazil, Chile, Colombia, Costa Rica, Dominican Rep, Ecuador, El Salvador, Guatemala, Haiti, Honduras, Mexico, Nicaragua, Panama, Paraguay, Peru, Spain, Uruguay, Venezuela
R01CA269472 Sujha Subramanian Research Triangle Institute  An integrated Community-Clinic Model of Optimized Implementation Strategies to Increase Early Detection of Breast and Cervical Cancers in Kenya Kenya
U01CA275053 Rebecca G Nowak, Sylvia Adebajo University of Maryland Baltimore, Institute of Human Virology, Nigeria Integrated Model for the Prevention of Anal Cancer using Screen and Treat for HSIL (IMPACT) Nigeria
U01CA275113 Lisa C Flowers, Oliver Ozechi, Olutosi Awolude, Laura Gaydos, Olabank Ogunsola Emory University, APIN Public Health Initiatives Ltd/Gte  The CHESS (Community, Home-based Education, Screening Services) Strategy to Increase Cervical Cancer Control Access for HIV-positive Women in Nigeria Nigeria
U01CA275054 Sujha Subramanian, Michael Mbizvo, Catherine Mwaba Research Triangle Institute, Clinical and Radiation Oncology Society of Zambia (ZASCRO) Integrated Delivery of Cancer Control Interventions for Adolescents and Young Adults Living with HIV in Zambia Zambia
U01CA275118 Gregory Aarons, Echezona Ezeanolue University of California, San Diego, University of Nigeria ACCESS: Accelerating Cervical Cancer Elimination Through the Integration of Screen-and-treat Services Nigeria
U01CA275032 Surbhi Grover, Katharine Rendle University of Pennsylvania,  University of Botswana Thibang Diphatlha: Testing Adaptive Strategies to Close the Gap from Cervical Cancer Diagnosis to Treatment in Botswana Botswana
U01CA275048 Manhattan E Charurat, Seth Himelhoch, Bontle Mbongwe University of Maryland Baltimore, Botswana-UMSOM Health Initiative Botswana Smoking Abstinence Reinforcement Trial (BSMART) Botswana
U01CA275033 Jean Marie Hunleth, Michelle Silver Washington University, Tropical Disease Research Centre Leveraging HIV Infrastructure to Implement Cervical Cancer Prevention: A Study to Integrate HPV Vaccination in Adolescent HIV Clinics in Zambia Zambia
U01CA275129 Lifang Hou, Jane Holl, Mamoudou Maiga Northwestern University at Chicago, Jos University Teaching Hospital, University of Ibadan, Universite des Sciences, des Techniques et des Technologies
West Africa Self-Sampling HPV-based Cervical Cancer Control Program (WA-SS-HCCP) for WLWHA: Barriers, Challenges, and Needs Nigeria and Mali


How to Connect

CGH collaborates with NCI’s Division of Cancer Control and Population Sciences (DCCPS). For more information, see DCCPS’ Implementation Science team

For information on implementation science and HIV in low- and middle-income countries, contact Vidya Vedham, Ph.D., at