Significant challenges exist in understanding and tackling tumor heterogeneity across the initiation-progression-resistance spectrum. Central to this challenge is cellular plasticity, which covers wide-ranging adaptive responses and biological endpoints throughout the course of early lesion progression to tumor formation and response to therapy.
Although epigenetic, transcriptomic, and metabolic mechanisms have been associated with cellular plasticity, the molecular underpinnings are still not well understood, highlighting the need to better understand the factors underlying these critical cell state transitions.
The Workshop on Understanding Plasticity and its Role Across the Cancer Continuum was held on September 23 -24, 2026 to identify roadblocks and challenges in improving our knowledge of the molecular mechanisms underlying plasticity, and to raise awareness of the significance of cell plasticity in cancer initiation, progression, and treatment response.
Documents from the Workshop
Contacts for the Workshop
For additional information about the Workshop, please contact Dr. Ruibai Luo or Dr. Natalia Mercer.