The goal of the Next-Generation Technologies for Next-Generation Cancer Models Program (funded through RFA-CA-19-055) was to facilitate the use of Human Cancer Models Initiative (HCMI) models by the research community.
New tools and the broader use of next-generation cancer models through the program aimed to contribute to advances in understanding important pathways in cancer initiation and progression, as well as drug response and resistance.
Contact for the Program
For additional information about the Next-Generation Technologies for Next-Generation Cancer Models Program, please contact Dr. Liming Yang.
Past Projects
| Institution | Principal Investigator(s) | Project Title |
|---|---|---|
| Broad Institute | John G. Doench | Advanced tools for HCMI model genetic perturbation and metastasis characterization |
| Dana-Farber Cancer Institute | William C. Hahn | Development and implementation of multiplex methods to understand the biology and heterogeneity of patient-derived cancer models |
| Massachusetts Institute of Technology | Bonnie Berger, Omer Yilmaz | Developing high-throughput genetic perturbation strategies for single cells in cancer organoids |