Past Division of Cancer Biology Research Programs
DCB funded past research programs that supported emerging areas in cancer biology and advanced basic cancer research.
Past Programs from DCB
-
Alliance of Glycobiologists for Cancer Research
Determined the biological mechanisms that alter glycosylation to promote cancer and developed glycan-based markers that can be used for the early detection of cancer.
-
Barrett's Esophagus Translational Research Network (BETRNet)
Centralized and enhanced efforts to understand Barrett's esophagus (BE) and to prevent esophageal adenocarcinoma (EA).
-
Cancer Genome Characterization Initiative (CGCI)
Supported research to comprehensively catalog the genomic alterations in rare adult and pediatric cancers.
-
Clinical Trial Sequencing Program (CTSP)
Promoted the use of genomics in NCI-sponsored clinical trials of the National Clinical Trials Network (NCTN).
-
Genomic Data Analysis Network (GDAN)
Leveraged the genomic data and resources produced by NCI for the benefit of cancer patients.
-
Molecular Characterization of Screen-Detected Lesions (MCL)
Comprehensively characterized cellular and molecular components of early lesions.
-
New Approaches to Synthetic Lethality for Mutant KRAS-Dependent Cancer
Used next-generation approaches to identify new strategies to treat KRAS-driven cancers.
-
Next-Generation Technologies for Next-Generation Cancer Models
Facilitated the use of Human Cancer Models Initiative (HCMI) next-generation cancer models.
-
Patient-Derived Models of Cancer (PDMC) Program
Developed and characterized patient-derived models to investigate the biological mechanisms that drive cancer phenotype and response to perturbations.
-
The Cancer Genome Atlas (TCGA)
Molecularly characterized over 20,000 primary cancer and matched normal samples spanning 33 cancer types.
-
Therapeutically Applicable Research to Generate Effective Treatments (TARGET)
Applied a comprehensive genomic approach to determine molecular changes that drive childhood cancers.
-
Tumor Microenvironment Network (TMEN)
Advanced the understanding of a tumor’s interactions with its surrounding microenvironment.