hereditary predisposition
(heh-REH-dih-tayr-ee PREE-dih-spuh-ZIH-shun)
An increased chance or likelihood of developing a particular disease based on the presence of one or more genetic variants and/or a family history suggestive of an increased risk of the disease. Having a hereditary predisposition does not mean an individual will develop the disease. Lifestyle and environmental factors can also affect an individual's risk of disease. Also called genetic predisposition, genetic susceptibility, and inherited predisposition.